How Age Spot Remover Works

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Age spot remover may work in several ways, depending on the ingredients. Here’s a look at some of the common ingredients and what they do.


Arbutin is sometimes listed as bearberry or cranberry extract. It actually comes from the leaves of the plants, not from the berries themselves. The compound is one of several natural ingredients that have proven effectiveness for inhibiting melanin production.

Excessive melanin production is what causes the spots to form. The idea is that inhibiting melanin production will allow new cells to be produced that are lighter in color. Arbutin is an irritant and may cause side effects such as itching or redness.


Hydroquinone is a man-made chemical compound that is derived from benzene, a known human carcinogen. It works like Arbutin to inhibit melanin production. Like Arbutin, it can cause skin irritation.

If you had to choose between the two, Arbutin would be the best choice, because it has no carcinogenic activity. Hydroquinone is not available in some countries because of the possible cancer risks.

Nutgrass Root Extract

The effect of nutgrass root extract has not been attributed to a single compound. It does not contain Arbutin, but age spot remover containing nutgrass does inhibit melanin significantly; by as much as 41.4%. The big advantage of the extract is that it does not cause irritation. In fact, it is an anti-irritant that actually soothes the skin.

Coenzyme Q10

Coenzyme Q10 in a Nano-particle formulation can penetrate through the skin’s surface and into the deeper layers. It is believed to be the nutrients antioxidant activity that works to reverse free radical damage in the skin.

In addition to reducing hyperpigmentation, the ingredient may also be beneficial for reducing wrinkles and other visible signs of aging. No side effects are caused by coenzyme Q10, although other ingredients in the ointment, cream or lotion could cause irritation.

Bioactive Keratin

An age spot remover may contain bioactive keratin to help promote the production of new skin cells. A melanin inhibitor would need to be included to provide fast results.

There is at least one cream on the market that contains nutgrass root extract, coenzyme Q10 and bioactive keratin. The three ingredients are likely to provide the fastest benefits. Some users have seen results in just a few weeks. No age spot remover can work instantly. But if you are consistent and you also try to protect the area from the sun, you should see results, especially if it contains those last three ingredients.